Blood keto acid levels during intoxication with inhibitors of carbohydrate metabolism.
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چکیده
منابع مشابه
Physiological Disturbances during Experimental Diphtheritic Intoxication
In the first paper of this series (12) it was pointed out that during diphtheritic intoxication in rabbits there was evidence of liver disturbance, manifested by a marked rise in the amino-acid nitrogen which in the more severe intoxications was accompanied by a hypoglycemia. When smaller doses of toxin were injected the amino-acid nitrogen changed but little, while the blood sugar remained rel...
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The process of transamination takes place in many tissues in the body and is a fundamental mechanism in the metabolism of amino-acids. Basically it consists of the reversible transfer of an amino group from an amino-acid to a keto acid, providing a link between protein and carbohydrate metabolism. Although there appear to be a multitude of transamination systems, each catalysed by a specific en...
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Thiamine deficiency leads to a well-defined biochemical lesion of carbohydrate metabolism with increase in pyruvate and lactate in the blood (Peters, 1936). Since Lohmann & Schuster (1937) showed that thiamine in the ester form of pyrophosphate is the coenzyme for the decarboxylation of pyruvic acid, it has been found to participate in several important reactions of carbohydrate metabolism, in ...
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Pyruvic acid is a normal intermediary of carbohydrate metabolism (1, 2). It has been previously demonstrated that thiamin, or more particularly thiamin pyrophosphate (cocarboxylase), is concerned in the normal catabolism of pyruvic acid (1). In Oriental beri-beri (3) and peripheral neuropathy in the alcohol addict (4)-both diseases associated with a deficiency of thiaminhyperpyruvemia does occu...
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During and following the production of shock by hemorrhage in the normal, suprareno-demedullated, and suprarenalectomized rat, the following significant changes in amino acid and carbohydrate metabolism have been observed. 1. In the intact, suprareno-demedullated, and suprarenalectomized rat there is a progressive rise in the whole blood and plasma amino acid nitrogen levels during and after a ...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 61 2 شماره
صفحات -
تاریخ انتشار 1955